Preventing, Diagnosing, and Treating Postpartum Haemorrhage: A Practical Summary of WHO 2025 Recommendations
Introduction
Postpartum haemorrhage (PPH) remains the leading cause of maternal mortality globally, accounting for nearly one in five maternal deaths worldwide. The majority of these deaths are preventable through timely prevention, early diagnosis, and standardised treatment. Recognising persistent gaps in care, the World Health Organisation (WHO), in collaboration with the International Federation of Gynaecology and Obstetrics (FIGO) and the International Confederation of Midwives (ICM), released consolidated evidence-based guidelines in 2025 to harmonise global practice and accelerate reductions in maternal deaths.
This article summarises the key recommendations for the prevention, diagnosis, and treatment of postpartum haemorrhage, translating the guideline table into practical guidance for frontline health workers and health systems.
Understanding Postpartum Haemorrhage
Postpartum
haemorrhage is defined as excessive bleeding after childbirth,
usually within the first 24 hours. While traditional definitions focused on
volume alone, current guidance emphasizes objective blood loss
measurement combined with maternal clinical signs, recognizing that women
may deteriorate rapidly even at lower volumes of blood loss.
Because most
women who develop PPH have no identifiable risk factors, every
birth must be managed as potentially high risk, with preparedness for rapid
response.
Antenatal Interventions: Preventing PPH Before Birth
1. Prevention and Treatment of Anaemia
Anaemia
significantly worsens outcomes when postpartum bleeding occurs. WHO therefore
recommends:
- Full blood count testing as the preferred method
to diagnose anaemia during pregnancy.
- Daily oral iron and folic acid
supplementation (30–60
mg iron plus 400 μg folic acid) for all pregnant women.
- Intermittent iron–folic acid
supplementation where
daily dosing is poorly tolerated or anaemia prevalence is low.
- Intravenous iron therapy for women with moderate
to severe iron-deficiency anaemia when oral iron is ineffective or not
tolerated.
These
interventions strengthen maternal reserves and reduce the severity of
PPH-related complications.
Intrapartum Interventions: Reducing Risk During Labour
To
minimize trauma and bleeding during childbirth, the guidelines recommend:
- Perineal protection techniques (perineal massage, warm
compresses, controlled delivery of the head) based on a woman’s
preferences.
- Avoidance of routine
episiotomy,
which increases blood loss and perineal trauma.
These
measures support physiological birth while reducing preventable bleeding.
Postpartum Interventions: Preventing PPH After Birth
2. Universal Use of Uterotonics
The single
most effective intervention for PPH prevention is the routine use of
a quality-assured uterotonic during the third stage of labour. WHO
recommends one of the following:
- Oxytocin 10 IU IM or IV – first-line choice
where cold chain is reliable.
- Heat-stable carbetocin 100 μg
IM or IV –
preferred where cold chain cannot be guaranteed.
- Misoprostol 400–600 μg orally – effective alternative,
including for community-based births.
Notably:
- Ergometrine,
oxytocin–ergometrine combinations, and injectable prostaglandins are not
recommended for
PPH prevention.
- Sustained uterine massage is
not recommended when
prophylactic oxytocin has already been administered.
3.
Community and Out-of-Facility Births
Where
skilled birth attendants are unavailable:
- Community health workers may
administer misoprostol.
- Antenatal distribution of
misoprostol for
self-administration is recommended only with targeted monitoring
and evaluation.
Diagnosis
of Postpartum Haemorrhage: Early Detection Saves Lives
Timely
diagnosis is critical. The guidelines strongly recommend:
- Routine objective measurement
of blood loss for
all births, using tools such as calibrated drapes.
- Initiation of treatment when:
- Blood loss is ≥500 mL,
or
- Blood loss is ≥300 mL
with abnormal vital signs (tachycardia, hypotension, shock index
>1).
- Regular uterine tone
assessment to
identify uterine atony early.
The first
two hours after birth are particularly high-risk and require close
monitoring.
First-Response
Treatment of Postpartum Haemorrhage
Once PPH
is identified, immediate standardized response is essential.
Core
First-Line Treatments
WHO
recommends:
- Intravenous oxytocin as the first-line
uterotonic.
- Additional uterotonics (ergometrine,
oxytocin–ergometrine, or misoprostol) if bleeding persists.
- Uterine massage for treatment (distinct
from prevention).
- Early intravenous tranexamic
acid (TXA) within 3
hours of birth, in addition to standard care.
- Isotonic crystalloids for fluid resuscitation.
PPH
Treatment Bundle
A
standardized care bundle should include:
- Uterine massage
- Uterotonic administration
- Tranexamic acid
- IV fluids
- Genital tract examination
- Rapid escalation of care
This
bundle approach improves survival by reducing delays and variation in care.
Treatment
of Refractory Postpartum Haemorrhage
When
first-line measures fail, the following are recommended as temporizing
or definitive interventions:
- Bimanual uterine compression
- External aortic compression
- Non-pneumatic anti-shock
garment (NASG)
- Uterine balloon tamponade, provided strict safety
criteria are met
- Surgical interventions when conservative
measures fail
- Blood transfusion guided by clinical and
laboratory assessment
Uterine
packing with gauze is not recommended due to safety concerns.
Supportive
Care After PPH
Recovery
does not end once bleeding stops. WHO recommends:
- Oral iron supplementation for
6–12 weeks postpartum in
settings with high anaemia prevalence.
- Intravenous iron therapy for severe postpartum
anaemia when rapid correction is required.
This
reduces long-term morbidity and improves maternal well-being.
Health
System Interventions: Making PPH Care Sustainable
Effective
PPH management requires strong systems. Recommended actions include:
- Use of formal PPH prevention
and treatment protocols
- Clear referral pathways
- Simulation-based training for pre-service and
in-service health workers
- Monitoring uterotonic use as a quality-of-care
indicator
Health
systems must ensure reliable supply chains, trained personnel, and functional
referral mechanisms.
Conclusion
Postpartum
haemorrhage is a medical emergency that demands preparedness at every
birth. The 2025 WHO consolidated guidelines provide a clear,
evidence-based roadmap spanning antenatal care, childbirth, postpartum
management, and health system strengthening. Consistent implementation of these
recommendations—especially routine uterotonic use, objective blood loss
measurement, early tranexamic acid administration, and standardized treatment
bundles—can save thousands of mothers’ lives each year.
Ending
preventable maternal deaths from PPH is not a question of knowledge, but
of action, accountability, and system readiness.
Postpartum
Haemorrhage (PPH) in Kenya
Practical
Tables and Infographic Summaries Based on WHO 2025 Guidelines
Audience: County Health Management
Teams (CHMTs), facility in-charges, clinicians, nurses, midwives, CHPs/CHEWs,
implementing partners, and policy-makers.
INFOGRAPHIC
1: WHY PPH MATTERS IN KENYA
Postpartum
haemorrhage is:
- The leading cause of
maternal death in Kenya
- Responsible for deaths
in both facility and community births
- Often preventable with
low-cost, high-impact interventions
Key
message:
➡️ Every
birth must be managed as a potential PPH risk.
TABLE
1: ANTENATAL INTERVENTIONS (KENYA CONTEXT)
|
Intervention Area |
WHO Recommendation |
Practical Application
in Kenya |
|
Anaemia screening |
Full blood count preferred; Hb testing acceptable |
Use Hb meters in Level 2–4 facilities where CBC unavailable |
|
Iron–folate
supplementation |
Daily iron (30–60 mg) + folic
acid (400 μg) |
Integrate into ANC clinics and
community ANC outreaches |
|
Intermittent iron |
Weekly iron–folate where daily not tolerated |
Useful in adolescents and women with side effects |
|
IV iron therapy |
For moderate–severe anaemia |
Refer to Level 4–6 facilities
with trained staff |
County
Action Point:
Ensure uninterrupted iron–folate supply through KEMSA and
partner-supported last-mile delivery.
INFOGRAPHIC
2: THE MOST IMPORTANT PREVENTION STEP
🩺 USE A UTEROTONIC FOR EVERY BIRTH
One
woman. One birth. One uterotonic.
TABLE
2: UTEROTONIC OPTIONS FOR PPH PREVENTION IN KENYA
|
Uterotonic |
Dose & Route |
When to Use |
Kenyan Context |
|
Oxytocin |
10 IU IM/IV |
First choice |
Use in hospitals & health centres with cold chain |
|
Heat-stable
carbetocin |
100 μg IM/IV |
Where cold chain unreliable |
Ideal for hard-to-reach counties |
|
Misoprostol |
400–600 μg oral |
No injection or skilled staff |
For community & home births |
❌ Not
recommended:
- Ergometrine
- Oxytocin–ergometrine
combinations
- Injectable prostaglandins
INFOGRAPHIC
3: COMMUNITY BIRTHS (KENYA REALITY)
If
birth happens outside a facility:
- CHPs/CHEWs can
administer oral misoprostol
- Antenatal misoprostol
distribution allowed with monitoring
- Clear referral
pathways must exist
TABLE
3: DIAGNOSIS OF PPH – WHAT KENYAN FACILITIES SHOULD DO
|
Step |
Recommendation |
Facility-Level
Practice |
|
Blood loss measurement |
Objective measurement for all births |
Use calibrated drapes or standard containers |
|
Early trigger |
≥500 mL OR ≥300 mL + shock signs |
Act within first 2 hours
postpartum |
|
Uterine tone |
Routine uterine assessment |
Include in post-delivery monitoring charts |
County
Indicator:
% of deliveries with documented blood loss measurement
INFOGRAPHIC
4: FIRST 15 MINUTES SAVE LIVES
THE PPH
FIRST-RESPONSE BUNDLE
1️⃣ Uterine massage
2️⃣
Uterotonic (oxytocin first-line)
3️⃣
Tranexamic acid (within 3 hours)
4️⃣
IV fluids (crystalloids)
5️⃣
Genital tract examination
6️⃣
Escalate care immediately
TABLE 4: FIRST-RESPONSE TREATMENT OF PPH
|
Intervention |
Status |
Notes for Kenya |
|
IV oxytocin |
Recommended |
First-line in all facilities |
|
Additional
uterotonics |
Recommended |
Use if bleeding persists |
|
Tranexamic acid (TXA) |
Strongly recommended |
Stock in maternity & theatres |
|
Uterine massage |
Recommended |
Treatment only (not prevention) |
|
IV crystalloids |
Recommended |
Avoid colloids |
INFOGRAPHIC
5: WHEN BLEEDING DOES NOT STOP
REFRACTORY
PPH = ACT FAST + REFER
TABLE
5: MANAGEMENT OF REFRACTORY PPH
|
Intervention |
Use in Kenya |
|
Bimanual uterine compression |
Immediate temporizing measure |
|
External aortic
compression |
Useful in transit/referral |
|
NASG |
Ideal for Level 3–4 facilities & ambulances |
|
Uterine balloon
tamponade |
Use only where surgery &
blood available |
|
Surgery |
Refer urgently to Level 5–6 |
|
Blood transfusion |
Protocol-based, timely |
❌ Not
recommended: Uterine gauze packing
TABLE 6: POST-PPH SUPPORTIVE CARE
|
Intervention |
Recommendation |
Kenyan Practice |
|
Oral iron |
6–12 weeks postpartum |
Integrate into PNC clinics |
|
IV iron |
Severe anaemia |
Level 4+ facilities only |
INFOGRAPHIC
6: HEALTH SYSTEM ACTIONS FOR COUNTIES
STRONG
SYSTEMS = FEWER DEATHS
TABLE
7: COUNTY-LEVEL HEALTH SYSTEM INTERVENTIONS
|
Area |
Required Action |
|
Protocols |
Display PPH protocols in all maternity units |
|
Training |
Simulation drills every 6–12
months |
|
Referral |
Clear, functional referral pathways |
|
Monitoring |
Track uterotonic use & PPH
outcomes |
|
Supplies |
Ensure oxytocin, TXA, IV fluids always available |
CONCLUSION:
WHAT THIS MEANS FOR KENYA
Postpartum
haemorrhage deaths are largely preventable. For Kenya to
achieve SDG 3.1 and national maternal mortality reduction
targets:
- Every birth must receive a
uterotonic
- Blood loss must be measured,
not guessed
- Tranexamic acid must be used
early
- Counties must institutionalize
PPH bundles and drills
No
woman should die giving life.
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